Fullerenes as the carriers of compounds with amide bond.

Fullerenes are molecules created solely of carbon and have a highly unusual attributes. The smallest structure in the fullerene family is conformation C20, which consists of pentagonal rings only, resulting in its instability. The C60 is the first fullerene containing 12 pentagonal and 20 hexagonal rings in which pentagons do not share an edge. It results in good stability of the carbon cage. The structure of C60 is a truncated icosahedron, with two different bond lengths: the ones between two hexagons are shorter (bond CñC, length 1.44 ), then between a hexagon and a pentagon (double-bond C=C, length 1.39 ); average bond length is 1.4 (1ñ3). The attributes like structure, geometry, size and shape of carbon cages yield the possibility to use them as vehicles to carry substances with pharmacological activity to molecular target. The derivatives of fullerenes are classified into following categories according to their functionalization: endohedral fullerenes with active molecules residing inside the carbon cage, exohedral with wide variety of both inorganic and organic groups existing outside and connected to the fullerenesí exterior and heterofullerenes ñ when one or more carbon atoms that form the fullerene carbon cage are replaced by a non-carbon atom, i.e., a heteroatom.